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SCiftS

Southern California Food Industry Conference
 

November 12-14, 2009

Nutritional Genomics:

The Impact of Dietary Regulation of

Gene Function on Human Disease

 

Wayne R Bidlack, Ph.D.

Professor - Department Human Nutrition and Food Science

California State Polytechnic University, Pomona

 

Raymond Rodriguez, Ph.D.

Director - Center of Excellence in Nutritional Genomics

University of California, Davis

will be held at

Food Science and Technology Program

Human Nutrition and Food Science Department

Kellogg West Conference Center

 

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Today it is not uncommon to discuss the etiology of human disease in the context of genes, environment, and nutrition. With the sequencing of the human genome and the rapid scientific advances that followed, researchers have been able to explore the linkage between diet and those molecular processes that govern long-term health and disease outcomes. While the presence of a particular gene variant may indicate a predisposition to a particular disease, the expression of the disease phenotype will depend on the complex interplay between external factors and the molecular components that regulate expression of specific genes. To fulfill the promise of nutritional genomics, researchers must reconcile the diverse properties of dietary signals (metabolites and peptides) with our current knowledge of regulatory gene networks that control higher-order disease traits. In addition to increasing our understanding of the inherited basis of disease, nutritional genomics also promises to revolutionize the way we manage health and disease risk with genome based dietary recommendations and other lifestyle changes.

While knowledge of human genome sequence is required for nutritional genomics, it is not sufficient to fully understand diet x genome interactions and how they relate to diseases such as obesity, hypertension, type 2 diabetes, cardiovascular disease and cancer. Researchers will need a more integrative view of the human genome, and how it interacts with the environment, if they hope to understand the more subtle mechanisms by which nutritive and non-nutritive bioactives impact gene regulatory processes and the physiologies they control. With this understanding will come opportunities to develop nutritional interventions and dietary recommendations that will enable individuals to achieve optimal health earlier, and maintain it longer, with evidence-based nutrigenomic diets. The ultimate goal will be to use whole foods in our diet to prevent some of the catastrophic health outcomes currently overtaking our children and impacting their future health and longevity. This focus on personalized nutrition will have important implication for the agricultural and food industries.

The commercialization of nutritional genomic products and services is already underway. It is imperative, therefore, that leaders in health care, professional societies, and government agencies be aware of recent advances in nutritional genomics so they can properly evaluate the scientific merit of personalized diets and provide guidance to those consumer who wish to tailor their diets to their individual genetic makeup.

The primary goal of this conference will be to provide a platform for researchers, scientists, educators, dietitians, health care professionals and policy makers to discuss the current status of nutritional genomic research. Renowned experts in the field will address the latest scientific findings on the mechanisms underlying diet-genome interactions.

Click here to download Registration Form